ADVANCED PRP THERAPY
ProSmart® & ExoSmart® Systems
At Alton Pain Clinic, we provide Advanced Platelet-Rich Plasma (PRP) therapy using ProSmart® and ExoSmart® systems to optimise platelet concentration and regenerative potential, designed to support musculoskeletal repair, tendon and ligament healing, and degenerative joint conditions.
What Is Platelet-Rich Plasma (PRP)?
Platelet-Rich Plasma (PRP) is an autologous regenerative treatment derived from the patient’s own blood. Platelets contain bioactive growth factors that stimulate:
- Tissue repair
- Collagen production
- Angiogenesis (new blood vessel formation)
- Cellular regeneration
PRP is commonly used in pain management, orthopedics, musculoskeletal injuries, and degenerative joint conditions.
The clinical effectiveness of PRP depends heavily on how it is processed.
Advanced PRP Therapy
At Alton Pain Clinic, we provide Advanced Platelet-Rich Plasma (PRP) therapy using ProSmart® and ExoSmart® systems as part of our regenerative medicine approach to sports injuries and musculoskeletal conditions. This treatment is designed to support tendon and ligament healing, soft tissue repair, and degenerative joint concerns by optimising platelet concentration and biological activity. By enhancing the body’s natural healing response, Advanced PRP aims to assist recovery in both acute and chronic injury settings.
Precision Harvesting & Platelet Saturation
The effectiveness of PRP therapy depends on how the plasma is harvested and concentrated. At Alton Pain Clinic, ProSmart® and ExoSmart® utilise controlled, protocol-driven centrifugation to isolate the platelet-rich fraction while minimising red blood cell and leukocyte contamination.
These systems are designed to achieve platelet saturation levels of up to approximately 93% within the processed plasma fraction, according to technical system data. Higher platelet concentration may support improved growth factor availability and regenerative signalling within injured musculoskeletal tissues.
By combining precision harvesting with optimised saturation, Advanced PRP provides a standardised plasma preparation intended to support tissue repair in sports-related and degenerative conditions.

ProSmart® PRP Technology
ProSmart® is a protocol-driven PRP system engineered to standardise and optimise platelet concentration. It is available in 2 ml, 4 ml, and 6 ml preparation kits, allowing tailored treatment volumes based on clinical indication.
Key Advantages:
- Controlled, multi-phase centrifugation
- High platelet concentration
- Reduced red blood cell contamination
- Standardised preparation technique
- Reproducible clinical quality
Published technical data associated with advanced PRP systems like ProSmart® demonstrate platelet saturation levels reaching up to 93% within the processed plasma fraction, significantly higher than many generalised systems.
This higher saturation translates into:
- Increased growth factor density
- Stronger regenerative signaling
- More reliable tissue healing response
ExoSmart® Advanced PRP Processing
ExoSmart® represents an evolution in regenerative plasma therapy. In addition to platelet concentration, this system optimises the biologically active components within plasma, including exosome-rich fractions that enhance cellular communication and repair mechanisms.
Clinical Benefits:
- Enhanced growth factor profile
- Optimised cellular signaling
- Reduced inflammatory contaminants
- Improved regenerative cascade activation
- Greater biological precision
ExoSmart® is particularly beneficial in complex musculoskeletal and degenerative conditions where maximising biologic potency is critical.
The Limitation of Generalised PRP
Traditional or generalised PRP systems typically involve a basic centrifugation process to separate plasma from whole blood. However, these methods may result in:
- Variable platelet concentration
- Inconsistent plasma purity
- Red blood cell or leukocyte contamination
- Unstandardised platelet saturation
- Unpredictable clinical outcomes
Because preparation protocols differ widely, the final injectable product may lack optimal regenerative potency.
| Clinical Parameter | Generalised PRP | ProSmart® PRP | ExoSmart® PRP |
|---|---|---|---|
| Platelet Concentration | Variable | High & standardised | High & optimised |
| Platelet Saturation | Inconsistent | Up to 93% (published technical data) | Up to 93% with enhanced biologic optimisation |
| Plasma Purity | Variable | High | Very High |
| Growth Factor Output | Moderate | Elevated | Enhanced & biologically optimised |
| Clinical Predictability | Variable | Consistent | Highly consistent |
| Regenerative Potential | Moderate | Strong | Advanced |
What Our Patients Say
Procedure Protocol at Alton Pain Clinic
Every PRP procedure at Alton Pain Clinic follows a structured medical protocol:
- Patient Evaluation – Comprehensive assessment to determine candidacy.
- Blood Collection – A controlled venous blood draw is performed.
- Precision Centrifugation – Blood is processed using ProSmart® or ExoSmart® systems under standardized parameters.
- Plasma Isolation – The platelet-rich layer is carefully harvested to maintain high purity and concentration.
- Targeted Injection – PRP is administered to the affected area, under ultrasound guidance for accuracy.
- Post-Procedure Guidance – Individualized recovery protocol provided.
The difference lies not only in the injection — but in the precision of the harvesting and processing technique.
Why Alton Pain Clinic Chooses Advanced PRP Systems
At Alton Pain Clinic, we deliver regenerative treatments grounded in clinical assessment and standardised protocols. Using ProSmart® and ExoSmart® processing systems, our approach is designed to produce consistent platelet-rich plasma preparations suitable for musculoskeletal and sports-related conditions.
It is recognised that PRP systems vary, and the method of centrifugation and harvesting can influence the composition and concentration of the final plasma product.
Your Care Pathway with us
- To book an appointment you can call our reception line, 0142084487, or email to info@altonpainclinic.co.uk or click the button given below.
- Comprehensive consultation and assessment for Advanced PRP therapy.
- Comprehensive consultation and assessment for regenerative musculoskeletal conditions.
- Same-day Advanced PRP treatment for tendons, joints, and soft tissue injuries.

Frequently Asked Questions
PRP therapy using ProSmart® or ExoSmart® systems produces highly concentrated, platelet-rich plasma to support tissue repair and musculoskeletal regeneration.
Advanced PRP uses precise multi-step centrifugation to increase platelet saturation (up to 93%) and produce a purer, more consistent plasma.
Higher platelet saturation increases growth factor levels, enhancing regenerative effects and tissue healing.
Blood is drawn and processed under controlled protocols to isolate the platelet-rich layer while reducing contamination from red blood cells and white blood cells.